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Please use this identifier to cite or link to this item: http://hdl.handle.net/UCSP/15865
Title: Diagnostic capacity and preliminary evaluation of Clock drawing Test, to order criteria from Cacho's version, for patients with mild Alzheimer's disease in Chilean population [Capacidad diagnóstica y validación preliminar del test del reloj, versión de cacho a la orden, para enfermedad de Alzheimer de grado leve en población chilena]
Authors: López, Norman
Allegri, Ricardo
Soto Añari, Marcio Fernando
Keywords: age;aged;Alzheimer disease;Article;Chilean;clinical article;clock drawing test;cognition;controlled clinical trial;controlled study;diagnostic test accuracy study;diagnostic value;discriminant validity;disease severity;educational status;female;human;male;Mini Mental State Examination;sensitivity and specificity
Issue Date: 2014
Publisher: Fundacion para la difusion neurologica en Ecuador - FUNDINE
metadata.dc.relation.uri: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84976385754&partnerID=40&md5=53fa6cf5c7e2c50e1d7474ff3d5f9da3
Abstract: Background: To perform a study with discriminant power and validity using the Clock drawing Test by instruction (CDTI) in patients with mild Alzheimer's disease (MAD). Materials and Methods: Phase I diagnostic test study. We included a healthy control arm of 58 elderly people and 40 cases with mild Alzheimer's disease. All participants were examined and diagnosed by clinical consensus. The MMSE, CDTI and clinical record were obtained. Results: There were significant differences between the study groups regarding cognitive tests' performance when comparing age and education, but no differences were found when comparing gender. ANCOVA test showed no significant effect exerted by the demographic variables on cognitive performance in any group. The sensitivity (CTO=84[%] vs MMSE=79, 3[%]), specificity (92, 5[%] vs 82, 5[%]) and diagnostic utility of the CDTO were higher than one's resulting form the MMSE (=0, 90, p=0, 000). The combined use of both instruments increased diagnostic capacity. The best cutoff point for the diagnosis of mild dementia was ≤ 6 points in CDTO and ≤ 23 in MMSE. Both instruments correlated statistically. Conclusions: The CTO is a useful test and can discriminate between cognitively healthy subjects and patients with EAL when appliying the "to order" criteria from Cacho's version.
URI: http://repositorio.ucsp.edu.pe/handle/UCSP/15865
ISSN: 10198113
Appears in Collections:Artículos de investigación

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